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Important announcement

🚨 NEWS🚨

China’s NMPA approves an IND application for IASO208, an in vivo, lentiviral vector-based, CD20-targeted CAR T-cell therapy, for the treatment of patients with R/R B-cell non-Hodgkin lymphoma.

Read more: https://prn.to/4kb1IhL

More drug updates

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Important announcement
@FDA grants regenerative medicine advanced therapy and fast track designations to prizloncabtagene autoleucel (A-CAR039), an investigational autologous bispecific CD20/CD19-directed CAR T-cell therapy, for the treatment of patients with R/R LBCL. Read more: https://bit.ly/4sQW5Ym
Important announcement
@FDA grants 510(k) clearance to two ready-to-use flow cytometry clinical tests to aid the identification and diagnosis of B-cell NHL and CLL. Read more: https://prn.to/4sS1BtI
Important announcement
@FDA accepts and grants priority review to the supplemental new drug application for zanubrutinib, a BTK inhibitor, in combination with rituximab for the treatment of adults with previously untreated MCL. Read more: https://bit.ly/4sFQGU5
Important announcement
The phase I/II PALISADES-1 (NCT04989803) and phase III PALISADES-2 (NCT07479797) trials evaluating KITE-753, an investigational anti-CD19/CD20 CAR T-cell therapy, for the treatment of R/R DLBCL have been placed on partial clinical hold to evaluate differences in ICANS observed between the phase I and II safety findings. Read more: https://bit.ly/3WofhR8