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Adcetris® (brentuximab vedotin) has been approved by the European Commission for CD30-positive CTCL 

By Sara Valente

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Jan 22, 2018


It was announced in a press release on 22nd January 2018, that the European Commission has approved Adcetris® (brentuximab vedotin) for the treatment of CD30-positive cutaneous T-cell lymphoma (CTCL) in adults after at least one prior systemic therapy. 

The European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion for this indication in November 2017. This followed results from the ALCANZA trial in which brentuximab vedotin demonstrated significantly superior clinical outcomes in patients with CD30-expressing CTCL versus physician's choice

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Which of the following would most increase your confidence in referring patients with R/R large B-cell lymphoma for CAR T-cell therapy?