44th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), 18-21 March 2018, Lisbon, Portugal
Institute Paoli-Calmettes, Marseille, FR
- Bechara Mfarrej discusses cytokine release syndrome (CRS) that is a potentially serious side-effect of CAR-T therapy.
- He explains that these side-effects are managed by supportive care but it is important to control the symptoms without eliminating the CAR-T cells.
- Most toxicities are manageable with dedicated supportive care, he concluded, and cytokine blocking medication can be given in the most extreme cases.