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SubtypesTherapeuticsCongressesTrialsExpert OpinionsDRUG UPDATES
2019-06-19T08:54:17.000Z

EHA 2019 | GOYA trial: Prognostic value of metabolic tumor volume in DLBCL

By Emily Smith, Marek Trněný
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Marek Trněný
Jun 19, 2019
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At the 24th Congress of the European Hematology Association (EHA), Marek Trněný from the Charles University General Hospital, Prague, CZ, talks about GOYA trial and the prognostic value of metabolic tumor volume in diffuse large B-cell lymphoma (DLBCL).

Marek Trněný highlights one of the main questions in the field; how do we manage patients failing therapy and how can we define refractory patients? Whilst the GOYA study was negative, one thing the group evaluated was how to identify refractory patients or those at risk of early relapse (within 12 months).
 
One method to do this was to measure total metabolic tumor volume. The group found that patients in 4th quartile had a higher chance of developing refractory disease and so defined a cut-off to predict this. It was concluded that if this cut-off is applied to daily practice, it may be possible to start subsequent treatment earlier or use more intensive treatment in these patients.

GOYA trial: Prognostic value of metabolic tumor volume in DLBCL

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Aggressive B-cell lymphomasDiffuse large B-cell lymphomaEHA 2019GOYAObinutuzumabRituximab

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