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EHA2026 | Top abstracts: What’s hot in lymphoma and CLL

By Dylan Barrett

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Jun 5, 2026

Learning objective: After reading this article, learners will be able to cite a new clinical development in lymphoma and CLL.


To help navigate the exciting content being presented at the European Hematology Association (EHA) 2026 Congress, June 11–14, 2026, Stockholm, SE, the Lymphoma Hub Steering Committee members have provided their recommendations for the top abstracts to look out for in lymphoma and CLL.

EHA 2026 | Top abstracts in lymphoma and CLL

Oral presentations: Thursday, June 11, 2026
Abstract TitlePresenterTime (CEST)
S226Safety and efficacy of subcutaneous mosunetuzumab plus lenalidomide induction therapy followed by mosunetuzumab maintenance in previously untreated follicular lymphomaEmmanuel Bachy17:00–17:15
S227Golcadomide (GOLCA), a potential, first-in-class, oral CELMoD ±rituximab (R) in patients (pts) with relapsed/refractory (R/R) follicular lymphoma (FL): Phase (Ph) 1/2 study long-term follow-up (f/u)Daniel Morillo17:15–17:30
S228Surovatamig (AZD0486) plus rituximab in previously untreated follicular lymphoma (FL): Initial safety data from the phase 3 SOUNDTRACK-F1 trialChan Y. Cheah17:30–17:45
S229Clinically relevant subgroup analysis from the randomized phase 3 EPCORE FL-1 trial: Treatment (Tx) effect of epcoritamab with lenalidomide and rituximab (R²) in R/R follicular lymphoma (FL)Benoit Tessoulin17:45–18:00
S245VT-EBV-N as post-remission therapy significantly improves disease-free survival in EBV-positive extranodal NK/T-cell lymphoma: A randomized, double-blind phase 2 trialDeok-Hwan Yang16:45–17:00
S248Brentuximab vedotin plus CHP plus etoposide (CHEPA) in newly diagnosed CD30- positive peripheral T-cell lymphomas with integrated ctDNA analysis: Primary results of the phase 2 CHEPA trialMarek Trněný17:30–17:45
S249High-dose methotrexate does not reduce risk of CNS relapse in ultra high-risk large B-cell lymphoma: An international retrospective analysis of 1,923 patientsMatthew R. Wilson17:45–18:00

 

Oral presentations: Friday, June 12, 2026
Abstract TitlePresenterTime (CEST)
S145First-line treatment of CLL/SLL with the all-oral combination of sonrotoclax and zanubrutinib achieves undetectable minimal residual disease rates of >90%, including in patients with del(17p)/TP53Chan Y. Cheah17:15–17:30
S146Venetoclax-obinutuzumab for previously untreated chronic lymphocytic leukemia: Final results of the randomized CLL14 studyKirsten Fischer17:30–17:45
S148A phase 2 study of fixed-duration pirtobrutinib and obinutuzumab in previously untreated CLLInhye E. Ahn18:00–18:15
S149Genetic biomarkers predicting sustained efficacy of venetoclax-based therapies or CIT in chronic lymphocytic leukemia: Final 5‑year analysis of the GAIA/CLL13 trialEugen Tausch18:15–18:30
S221Final analysis of the GHSG HD21 older cohort: Efficacy, survival and late toxicity of PET-guided BrECADD in older patients with advanced-stage classic Hodgkin lymphomaJustin Ferdinandus17:30–17:45
S222Avelumab in the front-line treatment of advanced classical Hodgkin lymphoma (AVENuE)- Final 3-year results of phase II studyAisling Barrett17:45–18:00
S235Results from EPCORE DLBCL-1: Randomized phase 3 study of epcoritamab (EPCOR) vs investigator’s choice chemoimmunotherapy (CIT) in patients with relapsed/refractory large B-cell lymphoma (R/R LBCL)Christopher P. Fox17:15–17:30
S236Vispa-cel, an allogeneic anti-CD19 CAR-T cell therapy with a PD-1 knockout, in patients with relapsed/refractory B cell non-Hodgkin lymphoma (ANTLER phase 1 clinical trial)Stephen Schuster17:30–17:45
S238Safety data and initial pooled efficacy data from the Nordic Lymphoma Group phase 3 POLAR BEAR trial in elderly or frail patients with diffuse large cell lymphoma - R-Pola-mini-CHP vs. R-mini-CHOPMats Jerkeman18:00–18:15
S239Golcadomide (GOLCA), a potential, first-in-class oral CELMoD + Pola-RCHP in patients (pts) with newly diagnosed aggressive B-cell lymphoma (A-BCL): Safety and 12-month efficacy from a phase 1b studyMaria Bouzani18:15–18:30

 

Oral presentations: Saturday, June 13, 2026
Abstract TitlePresenterTime (CEST)
S101Tafasitamab plus lenalidomide and R-CHOP for patients with previously untreated diffuse large B-cell lymphoma (DLBCL): Results from the phase 3 frontMIND studyGeorg Lenz12:30–12:45
S241Comprehensive analysis of bridging to CAR T-cell therapy in large B-cell lymphoma with conventional treatment or CD3XCD20 bispecific antibodiesRuth Fluemann17:30–17:45

 

Oral presentations: Sunday, June 14, 2026
Abstract TitlePresenterTime (CEST)
LB5001Fixed-duration pirtobrutinib plus venetoclax–rituximab versus venetoclax–rituximab for patients with previously treated CLL/SLL: A phase 3, randomized trial (BRUIN CLL-322)Matthew Davids09:15–09:30
LB5006First-in-human trial of LB2501, an in vivo CD19/CD20 dual targeting CAR-T therapy, in relapsed/refractory B-cell NHLLei Fan10:30–10:45
S150Updated efficacy and safety data from an ongoing phase 1a/b trial of the BTK degrader bexobrutideg (NX-5948) in patients with CLL across lines of therapyTalha Munir11:00–11:15
S152BGB-16673, a Bruton tyrosine kinase (BTK) degrader, in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL): A phase 1 CaDAnCe-101 study updateStephan Stilgenbauer11:30–11:45
S153Fixed duration venetoclax plus epcoritamab shows favorable tolerability and high response rates with early molecular responses in R/R CLL/SLL: Interim analysis of the randomized HOVON 165/AETHER trialArnon Philip Kater11:45–12:00
S232Fixed-duration glofitamab monotherapy in relapsed or refractory mantle cell lymphoma with or without prior Bruton's tyrosine kinase inhibitor exposure: Updated outcomes with 3.5 years of follow-upYasmin Karimi11:30–11:45
S256Circulating tumor DNA reveals lymphoma-associated mutations long before clinical diagnosisNick Veltmaat11:15-11:30

 

Posters 
Abstract TitlePresenterDate and time (CEST)
PF606Safety and efficacy of dose-modified approaches of fixed-duration (FD) ibrutinib+venetoclax (I+V) in patients with previously untreated CLL: Primary analysis of the prospective phase 2 TAILOR studyPaolo Ghia

Friday, June 12,

18:45–19:45

PF614Safety of fixed-duration (FD) acalabrutinib-venetoclax combinations in patients (pts) with chronic lymphocytic leukemia (CLL) stratified by age: Post hoc analysis of the phase 3 AMPLIFY trialJohn F. Seymour

Friday, June 12,

18:45–19:45

PF915A phase 1 study of the PRMT5 inhibitor AZD3470 in patients with relapsed/refractory classic Hodgkin lymphoma (PRIMAVERA)Pier Luigi Zinzani

Friday, June 12,

18:45–19:45

PF948Phase 3 inMIND study of tafasitamab plus lenalidomide and rituximab for relapsed or refractory follicular lymphoma: Clinical characteristics and outcomes of patients receiving second-line treatmentStefano Luminari

Friday, June 12,

18:45–19:45

PF963Five-year follow-up of patients with relapsed/refractory large B-cell lymphoma who achieved a complete response with glofitamab monotherapyKrish Patel

Friday, June 12,

18:45–19:45

PF968Mosunetuzumab plus polatuzumab vedotin versus rituximab, gemcitabine and oxaliplatin in large B-cell lymphoma: Updated efficacy and safety from the phase 3 SUNMO study including in patient subgroupsL. Elizabeth Budde

Friday, June 12,

18:45–19:45

PF975Zamtocabtagene autoleucel, a tandem CD20-CD19 directed CAR-T cell therapy in relapsed/refractory large B-cell lymphoma: Crossover analysis (third-line) from the randomized, pivotal DALY 2-EU trialPeter Vandenberghe

Friday, June 12,

18:45–19:45

PF977Sustained remissions beyond 4 years with epcoritamab monotherapy: Long-term follow-up results from the pivotal EPCORE NHL-1 trial in patients with relapsed or refractory large B-cell lymphomaCatherine Thieblemont

Friday, June 12,

18:45–19:45

PS1689Initial results of multicenter phase 2 BOVen-ΔMRD400 trial of zanubrutinib, obinutuzumab, and venetoclax (BOVen) with treatment duration guided by MRD kinetics (ΔMRD400) in treatment-naïve (TN) CLLJacob SoumeraiSaturday, June 13, 18:45–19:45
PS1701Pirtobrutinib in treatment-naïve patients with CLL/SLL: Pooled results from BRUIN CLL-313 and BRUIN CLL-314Jennifer WoyachSaturday, June 13, 18:45–19:45

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