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2021-07-09T08:33:17.000Z

How do cell-of-origin and molecular features influence outcomes in R/R DLBCL?

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Jul 9, 2021
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During the 16th International Conference on Malignant Lymphoma (16-ICML), the Lymphoma Hub spoke with Sanjal Desai, Mayo Clinic, Rochester, US. We asked, How do cell-of-origin and molecular features influence outcomes in relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL)?

How do cell-of-origin and molecular features influence outcomes in R/R DLBCL?

Desai describes a retrospective study investigating cell-of-origin using gene expression profiles or immunohistochemistry, and the influence on prognosis in patients with R/R DLBCL. This includes double-hit lymphoma (MYC and BCL2 and/or BCL6 rearrangements) and double-expressor lymphoma (MYC and BCL2 overexpression).

 

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