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Is CD47 a good target for immunotherapy in lymphoma?

During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the Lymphoma Hub spoke to Steven Horwitz, Memorial Sloan Kettering Cancer Center, New York, US. We asked, Is CD47 a good target for immunotherapy in lymphoma?

Is CD47 a good target for immunotherapy in lymphoma?

Horwitz discusses the unmet need for immunotherapy in lymphoma, and whether targeting CD47 could be a viable treatment strategy. He also gives an overview of early safety and efficacy data and outlines future research for CD47 targeting.

Dr. Horwitz has consulted, received honorarium from, or participated in advisory boards for; Acrotech Biopharma, C4 Therapeutics, Janssen, Kura Oncology, Kyowa Hakko Kirin, Myeloid Therapeutics, ONO Pharmaceuticals, Seattle Genetics, Takeda, Trillium Therapeutics, and Vividion Therapeutics.

Dr. Horwitz has received research support for clinical trials from ADC Therapeutics, Affimed, Aileron, Celgene, Daiichi Sankyo, Forty Seven, Inc., Kyowa Hakko Kirin, Millennium /Takeda, Portola Pharmaceuticals, Seattle Genetics, Trillium Therapeutics, and Verastem.

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