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Matthew WilsonDuring the COLYM 2022 Annual Meeting, the Lymphoma Hub spoke with Matthew Wilson, Beatson West of Scotland Cancer Centre, Glasgow, UK. We asked, Is central nervous system (CNS) prophylaxis warranted in DLBCL?
Is CNS prophylaxis warranted in DLBCL?
Wilson discusses the topic of CNS relapse in DLBCL and explains that there is a lack of data in support of a clear prophylactic treatment strategy. Wilson summarizes the latest data for the use of high-dose methotrexate and describes how it is may be used sparingly. Advancements in novel molecular techniques to screen patients at baseline for CNS disease hold great promise for guiding future prophylactic treatment regimens.
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This content is accurate as of the date of publication and is not updated retrospectively. Please refer to the latest available evidence, guidelines, and relevant regulatory information when making clinical decisions.
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When selecting the next therapy for patients with R/R MCL after BTKi progression, what is your most important consideration?