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Visual abstract | A phase III study of Zanubrutinib vs Bendamustine–Rituximab in CLL and SLL
The Lymphoma Hub is happy to present a visual abstract representing key data from the phase III SEQUOIA trial (NCT03336333), evaluating the efficacy and safety of zanubrutinib as a frontline therapy in chronic lymphocytic leukemia and small lymphocytic leukemia, compared with bendamustine-rituximab. Zanubrutinib, a covalent Bruton’s tyrosine kinase inhibitor, has previously shown efficacy in phase III studies of relapsed/refractory chronic lymphocytic leukemia. The Lymphoma Hub has previously reported on the safety and efficacy of zanubrutinib in marginal zone lymphoma.
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Which of the following would most increase your confidence in referring patients with R/R large B-cell lymphoma for CAR T-cell therapy?
