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#ASCO22

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Jun 3, 2022


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6 Aug 2022

👀 During #ASCO22, the Lymphoma Hub spoke with Alison Moskowitz, @NorthwellHealth. We asked, What are the latest treatment advances for Hodgkin #lymphoma?

👉 https://t.co/eBDWP1YK0o 👈

#lymsm #HL
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7 Jul 2022

🩺 During #ASCO22, the updated results with additional one year follow-up data on the CAPTIVATE trial in patients with #CLL/SLL were presented.

📚 Read our summary here
👉 https://t.co/Q6Kn9IIh4n 👈

#lymsm #leusm #leukemia
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9 Jun 2022

📢For all our live congress coverage from #ASCO22 check out our twitter moment!

📚If you want to see more, visit the Lymphoma Hub for drug updates, articles and interviews with key opinion leaders!

⭐️ https://t.co/pkONS3yOFS ⭐️

#lymsm #lymphoma

https://t.co/dxNPlVch3P
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7 Jun 2022

We hope you enjoyed following our live updates and congress coverage! 🎓

#ASCO22 was covered by us in Chicago, IL, as well as virtually!

Keep an eye on our socials for post-congress key points and insights! 📲

#medicalcongress #cancerawareness
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6 Jun 2022

CONGRESS #ASCO22 | Sattva Swarup Neelapu, MD @MDAndersonNews presents data from a phase I study of ADI-001 in adult patients with R/R advanced B-cell #lymphoma.

N=6
78% AEs were of grade 1/2
ORR=67%
CR=67%

#lymsm #medicalcongress #cancerawareness
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5 Jun 2022

CONGRESS #ASCO22 | Q&A: Hun Ju Lee, MD @MDAndersonNews asked about biological factors that may be contributing to the differential effect zilovertamab had in #CLL vs #MCL

A: It appears to be the complementary nature of inhibiting the BCR and ROR1 pathways together.

#lymsm
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5 Jun 2022

CONGRESS #ASCO22 | Q&A @michaelwangmd @MDAndersonNews was asked if they would recommend initiation of maintenance therapy if a patient converts to MRD+ following CAR-T.

A: MRD status is not yet ready to direct therapy. Eventually, this question could be answered using big-data.
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5 Jun 2022

CONGRESS #ASCO22 | Q&A @ChrisRFlowersMD, was asked about the significant drop in response rate in the crossover portion of the ROSEWOOD trial.

A: In part, we need to better understand the mechanisms of resistance in #FL, particularly in relation to single agent therapy.

#lymsm
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5 Jun 2022

RT @AML_Hub: CONGRESS #ASCO22 | @fravandi1 of @MDAndersonNews presents results of a phase II study of ASTX727 + ventoclax in patients with…
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4 Jun 2022

RT @gvhd_hub: CONGRESS #ASCO22 | Cole Harris Sterling @hopkinskimmel talks about PTCy for #GvHD prophylaxis in PTCL. N=65. 45% had GvHD, 2…
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4 Jun 2022

CONGRESS #ASCO22 | Ryan C. Lynch, MD of @UW presents results from a clinical trial of Pola-DA-EPCH-R in patients with aggressive B-cell #NHL (N=18)

The trial met it's primary safety endpoint with only 3 dose-limiting-toxicities observed.

#lymsm #cancerawareness #medicalcongress
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4 Jun 2022

CONGRESS #ASCO22 | @MarekTrnenyDr of @CharlesUniPRG presents an analysis of peripheral neuropathy using clinician- and patient-reported outcomes from the phase III POLARIX study

These findings support the use of Pola-R-CHP among patients with previously untreated #DLBCL

#lymsm
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4 Jun 2022

CONGRESS #ASCO22 | @GregNowakowski of @MayoClinic @MayoHemeOnc presents data from a retrospective cohort study of tafasitamab + lenalidomide vs systemic therapy in patients with R/R #DLBCL.

The combination may improve OS in certain patients.

#medicalcongress #cancerawareness
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4 Jun 2022

CONGRESS #ASCO22 | @AdamKittai of @OSUCCC_James describes racial and socioeconomic disparities among patients with #CLL

Black race was shown to be an independent prognostic variable for worse OS when controlling for the year of diagnosis and lower socioeconomic status.

#lymsm
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4 Jun 2022

CONGRESS @ASCO | @falchi_lorenzo of @MSKCancerCenter presents data from the phase I/II EPCORE NHL-2 trial of epcoritamab + RCHOP in patients with high-risk #DLBCL.

N=33
ORR=100%
CMR=77%

Therapy has a manageable safety profile; no new safety signals were detected.

#ASCO22
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4 Jun 2022

The @lymphomahub will be covering the following session today virtually:

Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia

Stay tuned for live updates, key insights, and interview coverage!

#ASCO22 #medicalcongress #cancerawareness #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | Q&A: @ErmannMD was asked whether the worse OS for Black pts was associated with the income level. A: In multivariate analysis even adjusting for income still showed a difference in OS however this was not seen in propensity matched analysis #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | Adrienne Alise Phillips @WeillCornell asks where are we today with disparities in #lymphoma? She discusses genetic analysis that the most frequently mutated driver genes in DLBCL differ by ancestry #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | @DrFredLocke @MoffittNews describes outcomes by ethnicity of pts with #LBCL given axi-cel. N=1389. ORR was 74% for White, 57% for African American, 67% for Asian & 73% for Hispanic pts. AA race was associated with worse ORR & CR rate vs White #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | @ErmannMD @UofUHealth presents the differences in treatment & survival for patients with #CLL of different racial minorities. Black pts had a shorter median OS of 7.0 yrs vs white pts (9.14 years). Black pts had higher rate of comorbidities #leukemia #leusm
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3 Jun 2022

CONGRESS #ASCO22 | @ErmannMD @huntsmancancer discusses racial disparities in OS in pts with #DLBCL. Compared to age-matched white pts, black pts age ≤60 had worse med OS (46 vs. 76 mos). Black race was associated with lower OS and pts were diagnosed younger #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | Q&A: Stephen Ansell @MayoClinic was asked how did Black pts on A+AVD fare vs white patients & other racial/ethnic minority groups? A: Race impacted survival with Caucasian pts doing better than other groups. Precise reason needs exploring #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | Alison J. Moskowitz @MSKCancerCenter discusses the history of NHL treatment and considers ongoing questions #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | @SharonCastelli2 @emoryhealthcare @EmoryMedicine describes AHOD1331 phase III study of children+AYA with advanced HL treated with Bv+AVE-PC vs AVE-PC. N=600. Median follow-up of 42.1 mos, 3-year EFS was 82.5% with ABVE-PC & 92.1% with Bv-AVE-PC #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | Stephen Ansell @MayoClinic reports on 6 year follow-up of the ECHELON-1 trial of pts with stage III/ IV cHL of A+AVD vs ABVD. OS favored A+AVD vs ABVD (p = 0.009). Estimated 6-year OS rates were 93.9% vs 89.4% with A+AVD vs ABVD, respectively. #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | @mike_dickinson1 @PeterMacCC was asked how patients who had been previously treated with CAR-T therapy fared versus CAR-T naïve pts? A: No difference was found in CR rates, responses seemed analogous #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | Kerry J Savage @UBC discusses the last 3 trials presented. She highlights response durability as important in the glofitamab trial. In PD-1/PDL inhibitors biomarkers of response are the key goal. SHINE supports BR + Ibr as option for NDMCL #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | @michaelwangmd @MDAndersonNews talks about the phase III SHINE trial of ibrutinib + bendamustine-rituximab +R maintenance for pts with #MCL. N=523. Median follow-up of 84.7 months. Med PFS of 80.6 months ibr + BR arm vs 52.9 mo in placebo +BR #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | Huiqiang Huang @uicc presents the data from GEMSTONE-201 evaluating an anti-PD-L1 mAb sugemalimab in R/R ENKTL. N=80 ORR was 46.2%; 29 pts achieved CR; 12-mo DoR rate was 86%. The 1- & 2-year OS rates were 68.6% and 54.6%, respectively #lymphoma #lymsm
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3 Jun 2022

CONGRESS #ASCO22 | @mike_dickinson1 @PeterMacCC speaks about the results of a phase II trial of glofitamab in patients with R/R #DLBCL treated with ≥2 lines of therapy. ORR & CR rates by IRC were 51.6% & 39.4%, respectively with a median follow-up of 12.6 months #lymphoma #lymsm
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3 Jun 2022

@ASCO starts today!

The Lymphoma Hub is covering ASCO virtually & in person!

The following session will be covered today:
Hematologic Malignancies-Lymphoma & Chronic Lymphocytic Leukemia

Keep an eye on our Twitter page for updates!

#ASCO22 #medicalcongress #cancerawareness
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31 May 2022

The @lymphomahub will be covering the 2022 ASCO Annual Meeting!

Date: 3–7 June
Location: Hybrid

Keep an eye on our socials for live coverage throughout the day from our virtual and in-person attendance in Chicago, IL! 🗣💻

#ASCO22 #medicalcongress #cancerawareness

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In practice, what is the most common reason you discontinue rituximab maintenance after BR in older patients with previously untreated MCL?