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Marco LadettoDuring the European School of Haematology (ESH)'s 2nd How to Diagnose & Treat Lymphoma conference, the Lymphoma Hub spoke to Marco Ladetto, SS Antonio e Biagio e Cesare Arrigo, Alessandria, IT, who discussed the role of autologous stem cell transplant (auto-SCT) for mantle cell lymphoma (MCL) in 2020.
Can we eliminate auto-SCT for patients with MCL?
Marco Ladetto starts by introducing what role auto-SCT plays in MCL and indicates that it must be considered in the context of full treatment protocols. He goes on to say, however, that medicine must continue to advance, and one way in which this can be done is through examination of the results of large phase III trials, such as TRIANGLE.
Ladetto discusses the heterogeneous nature of MCL and how different subsets respond to high-dose chemotherapy. The impact of some key mutations are also described.
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This content is accurate as of the date of publication and is not updated retrospectively. Please refer to the latest available evidence, guidelines, and relevant regulatory information when making clinical decisions.
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When selecting the next therapy for patients with R/R MCL after BTKi progression, what is your most important consideration?