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JULIET: What factors predict response to tisa-cel?
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During the 2021 TCT Meetings Digital Experience, the Lymphoma Hub spoke to Ulrich Jäger, Medical University of Vienna, Vienna, AT. We asked, What factors predict response to tisa-cel?
JULIET: What factors predict response to tisa-cel?
Jäger overviews a histopathologic analysis of the JULIET trial, which observed outcomes in patients with DLBCL receiving tisagenlecleucel (tisa-cel). He outlines the correlation of biological factors, including Myc expression, tumor infiltrating CD3 cells, and the quantity of LAG3 CD3+ T cells, with patient outcomes.
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