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JULIET: What factors predict response to tisa-cel?

Featured:

Ulrich JägerUlrich Jäger

Feb 18, 2021


During the 2021 TCT Meetings Digital Experience, the Lymphoma Hub spoke to Ulrich Jäger, Medical University of Vienna, Vienna, AT. We asked, What factors predict response to tisa-cel?

JULIET: What factors predict response to tisa-cel?

Jäger overviews a histopathologic analysis of the JULIET trial, which observed outcomes in patients with DLBCL receiving tisagenlecleucel (tisa-cel). He outlines the correlation of biological factors, including Myc expression, tumor infiltrating CD3 cells, and the quantity of LAG3 CD3+ T cells, with patient outcomes.