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The Lymphoma & CLL Hub is an independent medical education platform, sponsored by Beigene and Roche, and supported through educational grants from Bristol Myers Squibb, Ipsen Biopharmaceuticals, Lilly, Pfizer, and Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC View funders.
In chimeric antigen receptor (CAR) therapy, immune cells are taken from the patient, genetically modified to express the CAR construct, and then infused back into the patient. To date, most CAR therapies use engineered T cells, which express the targeted cancer cell antigen. New approaches explore the use of NK cells, allogeneic cell sources, and novel CAR constructs to optimize manufacturing and improve clinical outcomes.
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