All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional. If you are a patient or carer, please visit the Lymphoma Coalition.
Hypomethylating agents inhibit enzymes responsible for DNA methylation called DNA methyltransferases, which regulate gene expression. DNA methylation may lead to tumor suppressor gene silencing, and is considered as one of the mechanisms which can be targeted by hypomethylating agents to reduce tumor growth.