All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional. If you are a patient or carer, please visit the Lymphoma Coalition.
The Lymphoma Hub uses cookies on this website. They help us give you the best online experience. By continuing to use our website without changing your cookie settings, you agree to our use of cookies in accordance with our updated Cookie Policy
The Lymphoma Hub website uses a third-party service provided by Google that dynamically translates web content. Translations are machine generated, so may not be an exact or complete translation, and the Lymphoma Hub cannot guarantee the accuracy of translated content. The Lymphoma Hub and its employees will not be liable for any direct, indirect, or consequential damages (even if foreseeable) resulting from use of the Google Translate feature. For further support with Google Translate, visit Google Translate Help.
Histone modifiers
Histone modifiers
Histone deacetylation is an epigenetic process involved in the regulation of gene expression. Histone acetyltransferases and histone deacetylases (HDACs) have opposite functions, but both are involved in regulating a variety of oncogenic processes. HDAC inhibitors have anti-tumour activity and are used in various indications, such as T-cell lymphomas and mantle cell lymphoma (MCL).