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An expert panel hosted by
Customizing first-line BTK inhibitors for CLL
with Gilles Salles, Paolo Ghia, and Francesc Bosch
Wednesday, October 23, 2024
18:30-19:30 BST
This independent educational activity is supported by Pharmacyclics LLC, an AbbVie Company and Janssen Biotech. All content is developed independently by the faculty. The funder is allowed no influence on the content of this activity.
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T-cell engagers
T-cell engagers
Significant advances in antibody engineering have led to the development of a novel therapeutic class with a unique mechanism of action: to target both malignant cells and T cells and bring them closer together, activating the cytotoxic capacity of the immune cell. T-cell engagers include IgG-like bispecific antibodies and optimized designs without the Fc domain (BiTEs, DARTs, and TriKEs).
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