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Charles HerbauxDuring the 17th International Conference on Malignant Lymphoma (ICML), the Lymphoma Hub spoke with Charles Herbaux, University of Montpellier, Montpellier, FR. We asked, What are the key highlights from the descriptive analysis of the POLARIX trial (NCT03274492) in patients with diffuse large B-cell lymphoma (DLBCL).
Key highlights from a descriptive analysis of the POLARIX trial
POLARIX is a phase III trial investigating R-CHOP (cyclophosphamide, doxorubicin, prednisone, rituximab and vincristine) vs R-CHP (cyclophosphamide, doxorubicin, prednisone and rituximab) in combination with polatuzumab vedotin. Herbaux describes key results of the ad hoc analysis evaluating (1) the cause of death and prognosis of patients with primary refractory disease and (2) the prognosis of patients who are progression‐free at 24 m (PFS24) after 1L treatment.