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The Lymphoma & CLL Hub is an independent medical education platform, sponsored by Beigene and Roche, and supported through educational grants from Bristol Myers Squibb, Ipsen Biopharmaceuticals, Lilly, Pfizer, and Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC View funders.

2023-12-05T16:22:05.000Z

Phase III SELENE trial: efficacy and safety of ibrutinib plus BR/R-CHOP in R/R FL or MZL

Dec 5, 2023
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Learning objective: After reading this article, learners will be able to recall the efficacy and safety of ibrutinib in R/R FL or MZL.

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The Lymphoma Hub is excited to present a visual abstract representing key data from the phase III SELENE trial (NCT01974440) investigating the efficacy and safety of ibrutinib, plus bendamustine rituximab (BR) or rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP), compared with placebo plus BR/R-CHOP in adult patients with relapsed/refractory follicular or marginal zone lymphoma who received one or more prior lines of chemoimmunotherapy.1


 

 

Visual abstract

To download this visual abstract, click below.

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  1. Nastoupil LJ, Hess G, Pavlovsky MA, et al. Phase 3 SELENE study: ibrutinib plus BR/R-CHOP in previously treated patients with follicular or marginal zone lymphoma. Blood Adv. 2023. Online ahead of print. DOI: 10.1182/bloodadvances.2023010298 

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