Satellite Symposium | Treatment options for a patient with ibrutinib-resistant CLL

The virtual Lymphoma Hub Satellite Symposium, at the 16th International Conference on Malignant Lymphoma (16-ICML), saw a panel of international experts come together to discuss the sequencing of therapies in high-risk relapsed/refractory lymphoma and chronic lymphocytic leukemia (CLL). Professor Francesc Bosch, Vall d'Hebron Barcelona Hospital Campus, Barcelona, ES, discusses treatment options for a patient with ibrutinib-resistant CLL.

Bosch presents his treatment approach to a double-refractory ibrutinib-resistant patient case by firstly discussing the significance of predictive markers and how to use these to discern between different treatments. He then moves on to outline the therapeutic options for this case, including alternative BTK inhibitors, PI3 kinase inhibitors, and CAR T-cell therapy.