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Tafasitamab in DLBCL

Sep 28, 2020

During the 18th International Workshop on Non-Hogkin Lymphoma (iwNHL), the Chair of the Lymphoma Hub , Gilles Salles,Memorial Sloan Kettering Cancer Center, New York, US, spoke about the use of tafasitamab in patients with diffuse large B cell lymphoma (DLBCL).

Tafasitamab in DLBCL

Tafasitamab is a CD19-directed monoclonal antibody approved by the FDAin July 2020 for use in combination with lenalidomide as a second-line treatment for patients with relapsed or refractory (R/R) DLBCL. Approval was based on results from the phase II L-MIND study. In this interview, Gilles Salles discusses these results and questions how we might sequence the L-MIND regimen compared to chimeric antigen receptor (CAR) T cell therapy given that the epitope recognised by tafasitamab overlaps with the epitope targeted by CD19-directed CAR T cells.

Your opinion matters

At this year’s virtual ESH Meeting, the Lymphoma Hub Satellite Symposium will evaluate treatment options in patients with R/R DLBCL. What do you think is the most promising emerging therapy in this setting?
4 vote s - 16 hours left ...


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