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What do the ELM-2 results tell us about the efficacy of odronextamab for R/R DLBCL?

Featured:

Won KimWon Kim

Feb 10, 2023

Learning objective: After reading this article, learners will be able to cite a new clinical development in lymphoma.


During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the Lymphoma Hub was pleased to speak with Won Seog Kim, Sungkyunkwan University, Seoul, KR. We asked, What do the ELM-2 results tell us about the efficacy of odronextamab for relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL)?

What do the ELM-2 results tell us about the efficacy of odronextamab for R/R DLBCL?

Kim discusses results from the DLBCL cohort of the prospective phase II ELM-2 trial (NCT03888105) of odronextamab, which incorporated an optimized step-up regimen. He then highlights the promising efficacy and manageable toxicity profile of odronextamab in patients with R/R DLBCL.