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The Lymphoma & CLL Hub is an independent medical education platform, sponsored by Beigene and Roche, and supported through educational grants from Bristol Myers Squibb, Ipsen Biopharmaceuticals, Pfizer, and Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC View funders.

2023-02-10T10:37:56.000Z

What do the ELM-2 results tell us about the efficacy of odronextamab for R/R DLBCL?

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Feb 10, 2023
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Learning objective: After reading this article, learners will be able to cite a new clinical development in lymphoma.

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During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the Lymphoma Hub was pleased to speak with Won Seog Kim, Sungkyunkwan University, Seoul, KR. We asked, What do the ELM-2 results tell us about the efficacy of odronextamab for relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL)?

What do the ELM-2 results tell us about the efficacy of odronextamab for R/R DLBCL?

Kim discusses results from the DLBCL cohort of the prospective phase II ELM-2 trial (NCT03888105) of odronextamab, which incorporated an optimized step-up regimen. He then highlights the promising efficacy and manageable toxicity profile of odronextamab in patients with R/R DLBCL.

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