When is a second CAR T-cell infusion feasible for patients who failed prior CAR T-cell therapy?

During the 3rd European CAR T-cell Meeting, the Lymphoma Hub spoke to Jordan Gauthier, Fred Hutchinson Cancer Research Center, Seattle, US. We asked, When is a second CAR T-cell infusion feasible for patients who failed prior CAR T-cell therapy?

For patients who do not respond to the first round of CAR T-cell infusion, the best course of treatment is unknown but one option is to give a second dose. In this video, Jordan Gauthier discusses the data from 44 patients with B-cell malignancies.