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Which factors help guide therapy choice for R/R diffuse large B-cell lymphoma?
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During the EHA2021 Virtual Congress, the Lymphoma Hub spoke with Gilles Salles, Memorial Sloan Kettering Cancer Center, New York, US. We asked, Which factors help guide therapy choice for relapsed/refractory (R/R) diffuse large B-cell lymphoma?
Which factors help guide therapy choice for R/R diffuse large B-cell lymphoma?
In this video, Salles discusses insights presented during EHA2021 regarding the selection of patients with R/R diffuse large B-cell lymphoma for second-line therapy. Although autologous hematopoietic stem cell transplant (auto-HSCT) remains the standard of care, a recent randomized study is comparing auto-HSCT with chimeric antigen receptor (CAR) T-cell therapy. Salles also points out that the antibody-drug conjugate loncastuximab tesirine could be a feasible approach prior to treatment with CAR T-cell therapy.
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