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Which factors help guide therapy choice for R/R diffuse large B-cell lymphoma?

During the EHA2021 Virtual Congress, the Lymphoma Hub spoke with Gilles Salles, Memorial Sloan Kettering Cancer Center, New York, US. We asked, Which factors help guide therapy choice for relapsed/refractory (R/R) diffuse large B-cell lymphoma?

Which factors help guide therapy choice for R/R diffuse large B-cell lymphoma?

In this video, Salles discusses insights presented during EHA2021 regarding the selection of patients with R/R diffuse large B-cell lymphoma for second-line therapy. Although autologous hematopoietic stem cell transplant (auto-HSCT) remains the standard of care, a recent randomized study is comparing auto-HSCT with chimeric antigen receptor (CAR) T-cell therapy. Salles also points out that the antibody-drug conjugate loncastuximab tesirine could be a feasible approach prior to treatment with CAR T-cell therapy.

 

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