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ZUMA-12: Is CAR T-cell therapy effective in high-risk DLBCL as first-line therapy?

Featured:

Sattva NeelapuSattva Neelapu

Feb 17, 2021


During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the Lymphoma Hub spoke to Sattva Neelapu, MD Anderson Cancer Center, Houston, US, about the ZUMA-12 study. We asked, Is chimeric antigen receptor T-cell therapy effective in high-risk diffuse large B-cell lymphoma (DLBCL) as first-line therapy?

ZUMA-12: Is CAR T-cell therapy effective in high-risk DLBCL as first-line therapy?

Neelapu reports the promising results from the interim analysis of the phase II ZUMA-12 study, evaluating axicabtagene ciloleucel as first-line therapy in patients with high-risk DLBCL.


Your opinion matters

Which of the following would most increase your confidence in referring patients with R/R large B-cell lymphoma for CAR T-cell therapy?