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ZUMA 2: How does prior BTK inhibitor treatment affect the efficacy of KTE-X19 in patients with MCL?
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Michael WangDuring the Virtual 47th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the Lymphoma Hub spoke to Michael Wang, MD Anderson Cancer Center, Houston, US. We asked, How does prior BTK inhibitor treatment affect the efficacy of KTE-X19 in patients with MCL?
ZUMA 2: How does prior BTK inhibitor treatment affect the efficacy of KTE-X19 in patients with MCL?
Wang reports on data from the ZUMA 2 trial. He comments on the effect that prior exposure to Bruton's tyrosine kinase (BTK) inhibitors can have in patients with relapsed/refractory mantle cell lymphoma (MCL) being treated with KTE-X19.
Your opinion matters
Which of the following would most increase your confidence in referring patients with R/R large B-cell lymphoma for CAR T-cell therapy?