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An expert panel hosted by
Sequencing immune-based therapies in B-cell malignancies
with Ulric Jäger, Sagar Lonial, and Krina Patel
Saturday, June 15 | 18:00-19:30 CEST
Register nowThis independent education activity is sponsored by Bristol Myers Squibb. All content is developed independently by the faculty. Funders are allowed no direct influence on the content of this activity.
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During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the Lymphoma Hub spoke with Andrew Davies, University of Southampton, Southampton, UK. We asked, Can frontline treatment of DLBCL be improved by combining novel agents with R-CHOP?
Can frontline treatment of DLBCL be improved by combining novel agents with R-CHOP?
Davies begins by explaining how frontline therapies can be stratified according to biological risk factors and reviewing data on the potential benefit of augmented therapy in high-risk patients. Davies then discusses the impact of adding bortezomib to R-CHOP on overall and progression-free survival in patients with certain molecular subgroups of DLBCL. Finally, he reviews other novel therapies showing promise in combination with R-CHOP, including acalabrutinib and glofitamab.
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