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2021-01-27T15:08:06.000Z

Mosunetuzumab in heavily pretreated follicular lymphoma: Phase I dose-escalation trial updates

Jan 27, 2021
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Early phase studies of several novel bispecific antibodies are showing promising results for the treatment of R/R B-cell NHL. When considering bispecific antibody therapy, which characteristic/s would primarily drive your treatment choice?

Route of administration

13%

Safety

13%

Duration of treatment

8%

Efficacy

65%

23 votes

During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the Lymphoma Hub spoke to Sarit E. Assouline, Jewish General Hospital, Montreal, CA, about the use of mosunetuzumab in heavily pretreated follicular lymphoma.

Mosunetuzumab in heavily pretreated follicular lymphoma: Phase I dose-escalation trial updates

Assouline provides an update on a phase I trial evaluating mosunetuzumab, a bispecific CD3/CD20 antibody, in patients with relapsed/refractory follicular lymphoma. Assouline outlines the degree of activity, durability, and tolerability of the treatment and discusses future avenues for research.

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