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The Lymphoma & CLL Hub is an independent medical education platform, sponsored by Beigene and Roche, and supported through educational grants from Bristol Myers Squibb, Ipsen Biopharmaceuticals, Lilly, Pfizer, and Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC View funders.

2020-02-27T16:21:06.000Z

NICE recommends lenalidomide in combination with rituximab for patients with previously treated FL

Feb 27, 2020
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A novel combination therapy has been made available on the NHS for patients with previously treated follicular lymphoma (FL; Grade 13A). In the final appraisal document, the National Institute for Care Excellence (NICE) recommended the combination of lenalidomide with rituximab (R2) for adult patients with relapsed or refractory (R/R) FL. The R2 regimen offers a chemotherapy-free treatment that will become immediately accessible to patients with R/R FL.1

The Lymphoma Hub reported results from the phase III AUGMENT trial (NCT01938001) which led to the U.S. Food & Drug Administration (FDA) and European Medicines Agency (EMA) approval of R2 in adult patients with R/R FL. Take a look at the Lymphoma Hub’s coverage of the AUGMENT study, FDA approval and EMA approval of R2.

  1. Lenalidomide with rituximab for previously treated follicular lymphoma [ID1374]. https://www.nice.org.uk/guidance/gid-ta10323/documents/final-appraisal-determination-document. Issued; February 2020, [Accessed February 27, 2020]

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