Satellite Symposium | How to treat early relapse in a patient with FL

The virtual Lymphoma Hub Satellite Symposium, at the 16th International Conference on Malignant Lymphoma (16-ICML), saw a panel of international experts come together to discuss the sequencing of therapies in high-risk relapsed/refractory lymphoma and chronic lymphocytic leukemia. Professor Loretta J. Nastoupil, MD Anderson Cancer Center, Houston, US, discusses how to treat early relapse in a patient with follicular lymphoma (FL).

Nastoupil begins by outlining a clinical case and the benefits of utilizing PET scans to exclude transformation as the driver of poor outcomes. The presentation then reviews therapeutic options and the data that inform treatment selection, including data from the GADOLIN, AUGMENT, GALEN, and SWOG trials. Finally, Nastoupil describes how she would approach this case, utilizing available clinical trials that employ novel agents, such as tazemetostat and tafasitamab, and she offers insight for those that practice in a different setting.