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Monoclonal B-cell lymphocytosis

Monoclonal B-cell lymphocytosis

Monoclonal B-cell lymphocytosis (MBL) is a pre-leukemic form of chronic lymphocytic leukemia (CLL), characterized by a clonal B-cell presence in the absence of clinical symptoms and organ involvement, with < 5000 monoclonal B lymphocytes/µl in peripheral blood. Approximately 1−2% of patients with MBL progress to CLL, annually.

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